SPRR2G

Across TCGA cell cohorts, SPRR2G RNA expression is significantly associated with the go_rna of many other GO terms, with 349 significant associations in total. STOMACH shows the largest number of these associations.

The most reproducible SPRR2G-associated GO terms across cancer lineages are Cellular response to nutrient levels, Regulatory ncRNA-mediated post-transcriptional gene silencing, and Skin development. Each is linked with SPRR2G in more than 2 cancer types. Because this analysis shows association rather than direction, both SPRR2G-to-partner and partner-to-SPRR2G results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cellular response to nutrient levels grouped by SPRR2G-low versus SPRR2G-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SPRR2G→partner) and Y-score (partner→SPRR2G) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Cellular response to nutrient levels →	+0.073	+0.109	<.001	<.001	3	3
STOMACH	Regulatory ncRNA-mediated post-transcriptional gene silencing →	+0.089	+0.053	.002	.003	3	3
STOMACH	Skin development →	+0.081	+0.066	.006	.009	3	3
STOMACH	Carnitine biosynthetic process →	-0.096	-0.065	.004	.009	3	3
STOMACH	Termination of RNA polymerase II transcription →	+0.104	+0.053	.001	.003	3	3
LUNG_NSCLC_LUAD	Regulation of protein catabolic process at postsynapse, modulating synaptic transmission →	+0.135	+0.030	.003	.007	2	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 349 associations by consensus.

Cellular response to nutrient levels by SPRR2G expression — STOMACH

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