SPRR2D

Across TCGA patient cohorts, SPRR2D RNA expression is significantly associated with the protein abundance of many other proteins, with 7,705 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible SPRR2D-associated proteins across cancer lineages are SPRR1B, SPRR2D_S38, and ZNF185_S64. Each is linked with SPRR2D in more than 4 cancer types. Because this analysis shows association rather than direction, both SPRR2D-to-partner and partner-to-SPRR2D results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SPRR2D versus SPRR1B in LSCC, with a Pearson correlation of 0.82.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SPRR2D→partner) and Y-score (partner→SPRR2D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SPRR1B →	+1.902	+3.871	<.001	<.001	3	5
LSCC	SPRR2D_S38 →	+2.917	+4.162	<.001	<.001	3	5
LSCC	ZNF185_S64 →	+1.110	+2.989	<.001	<.001	3	4
PDAC	CLCA4 →	+2.311	+1.911	.009	.003	3	4
UCEC	DSG3 →	+1.673	+3.152	.001	.006	3	4
HNSC	GALM →	-0.507	-1.877	<.001	.003	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,705 associations by consensus.

SPRR2D vs SPRR1B — LSCC

Explore this scatter interactively →