SPRR2A

Across TCGA patient cohorts, SPRR2A RNA expression is significantly associated with the protein abundance of many other proteins, with 7,429 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible SPRR2A-associated proteins across cancer lineages are KRT16, KRT6A, and S100A7. Each is linked with SPRR2A in more than 4 cancer types. Because this analysis shows association rather than direction, both SPRR2A-to-partner and partner-to-SPRR2A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SPRR2A versus KRT16 in UCEC, with a Pearson correlation of 0.57.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SPRR2A→partner) and Y-score (partner→SPRR2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	KRT16 →	+1.594	+2.023	<.001	<.001	3	5
UCEC	KRT6A →	+1.787	+2.234	<.001	<.001	3	5
BRCA	S100A7 →	+1.697	+0.404	<.001	.001	3	4
HNSC	IVL →	+1.237	+2.012	<.001	<.001	3	4
UCEC	KRT17_S13 →	+1.415	+1.276	<.001	.009	3	4
LSCC	LY6D →	+1.835	+3.019	.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,429 associations by consensus.

SPRR2A vs KRT16 — UCEC

Explore this scatter interactively →