Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts
Across TCGA patient cohorts, SPRN mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.
The most reproducible SPRN-associated genes across cancer lineages are CD8+ naive T-cells and Th2 cells. Each is linked with SPRN in more than 1 cancer types. Because this analysis shows association rather than direction, both SPRN-to-partner and partner-to-SPRN results are reported.
Each partner links to its own Q-omics profile.
mutation associated genes by consensus
Ranked by combined sampling and lineage consensus. X-score (SPRN→partner) and Y-score (partner→SPRN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.