SPRING1P1

Across TCGA patient cohorts, SPRING1P1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,167 significant associations in total. STAD shows the largest number of these associations.

The most reproducible SPRING1P1-associated GO terms across cancer lineages are Negative regulation of protein localization, Regulation of protein binding, and Regulation of neuron apoptotic process. Each is linked with SPRING1P1 in more than 3 cancer types. Because this analysis shows association rather than direction, both SPRING1P1-to-partner and partner-to-SPRING1P1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of protein localization grouped by SPRING1P1-low versus SPRING1P1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SPRING1P1→partner) and Y-score (partner→SPRING1P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Negative regulation of protein localization →	+0.081	+0.034	<.001	<.001	3	4
STAD	Regulation of protein binding →	+0.084	+0.037	<.001	<.001	3	4
STAD	Regulation of neuron apoptotic process →	+0.064	+0.034	<.001	<.001	3	4
STAD	JNK cascade →	+0.071	+0.058	<.001	<.001	3	4
STAD	Positive regulation of apoptotic signaling pathway →	+0.077	+0.062	<.001	<.001	3	4
STAD	Hematopoietic progenitor cell differentiation →	+0.075	+0.031	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,167 associations by consensus.

Negative regulation of protein localization by SPRING1P1 expression — STAD

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