SPRING1P1

Across TCGA pan-cancer cohorts, SPRING1P1 RNA is linked to patient survival in 9 of 34 cancer types, making it the most broadly survival-associated SPRING1P1 data layer.

The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher SPRING1P1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated SPRING1P1 expression acts as an unfavorable survival marker.

SKCM, UCEC, and MESO are the cancer types where SPRING1P1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SKCM	DFS	Tertile	All	0.258	0.625	<.001	117	view →
UCEC	OS	Tertile	All	0.722	0.931	<.001	90	view →
MESO	OS	Tertile	III,IV	0.069	0.580	<.001	72	view →
THYM	DFS	Tertile	All	0.110	0.878	<.001	54	view →
OV	DFS	Tertile	II,III,IV	0.395	0.548	.017	54	view →
KIRP	DFS	Tertile	All	0.519	0.920	<.001	42	view →
LIHC	OS	Tertile	All	0.353	0.788	.003	36	view →
COAD	OS	Tertile	All	0.667	0.872	.010	30	view →
STAD	OS	Tertile	II,III,IV	0.481	0.739	.008	18	view →

Pink = unfavorable, green = favorable. Showing the 9 strongest of 9 lineages.

SPRING1P1–SKCM (DFS)

Open the SKCM breakdown →