SPOPL

Across TCGA patient cohorts, SPOPL RNA expression is significantly associated with the RNA expression of many other genes, with 20,866 significant associations in total. ACC shows the largest number of these associations.

The most reproducible SPOPL-associated genes across cancer lineages are LNPK, UBR3, and EAF1. Each is linked with SPOPL in more than 33 cancer types. Because this analysis shows association rather than direction, both SPOPL-to-partner and partner-to-SPOPL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SPOPL versus LNPK in UVM, with a Pearson correlation of 0.89.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SPOPL→partner) and Y-score (partner→SPOPL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UVM	LNPK →	+1.582	+1.188	<.001	<.001	3	34
UVM	UBR3 →	+1.497	+1.265	<.001	<.001	3	34
DLBC	EAF1 →	+1.059	+1.400	<.001	<.001	3	34
DLBC	GOLGA4 →	+1.595	+1.321	<.001	<.001	3	34
UVM	TMF1 →	+1.684	+1.218	<.001	<.001	3	34
UVM	TRMT10A →	+1.120	+1.279	<.001	<.001	3	34

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,866 associations by consensus.

SPOPL vs LNPK — UVM

Explore this scatter interactively →