SPON1

Across TCGA cell cohorts, SPON1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,757 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible SPON1-associated GO terms across cancer lineages are Endoplasmic reticulum to cytosol transport, Retrograde protein transport, ER to cytosol, and Protein exit from endoplasmic reticulum. Each is linked with SPON1 in more than 7 cancer types. Because this analysis shows association rather than direction, both SPON1-to-partner and partner-to-SPON1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endoplasmic reticulum to cytosol transport grouped by SPON1-low versus SPON1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SPON1→partner) and Y-score (partner→SPON1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Endoplasmic reticulum to cytosol transport →	+0.111	+1.089	<.001	.005	3	8
BONE	Retrograde protein transport, ER to cytosol →	+0.111	+1.089	<.001	.005	3	8
BONE	Protein exit from endoplasmic reticulum →	+0.112	+1.260	<.001	<.001	3	8
STOMACH	Establishment of protein localization to membrane →	+0.065	+1.409	<.001	.009	3	8
SKIN	Regulation of cell cycle G1/S phase transition →	+0.042	+0.283	.003	.005	3	8
BONE	Symbiont entry into host cell →	+0.118	+1.410	<.001	.009	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,757 associations by consensus.

Endoplasmic reticulum to cytosol transport by SPON1 expression — BONE

Explore this box plot interactively →