SPNS3

Across TCGA cell cohorts, SPNS3 RNA expression is significantly associated with the RNA expression of many other genes, with 6,592 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SPNS3-associated genes across cancer lineages are SPNS2, MAB21L4, and CATSPER1. Each is linked with SPNS3 in more than 13 cancer types. Because this analysis shows association rather than direction, both SPNS3-to-partner and partner-to-SPNS3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SPNS3 versus SPNS2 in KIDNEY, with a Pearson correlation of 0.63.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SPNS3→partner) and Y-score (partner→SPNS3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	SPNS2 →	+3.490	+1.458	<.001	.001	3	14
STOMACH	MAB21L4 →	+2.484	+1.529	<.001	<.001	2	7
LUNG_NSCLC_LUSC	CATSPER1 →	+1.684	+0.612	<.001	.003	3	6
OESOPHAGUS	ACSL5 →	+3.256	+0.663	<.001	.002	2	6
BLOOD_Lymphoma	SEL1L3 →	+3.500	+1.542	<.001	<.001	3	5
STOMACH	TMPRSS2 →	+3.349	+1.474	<.001	.004	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,592 associations by consensus.

SPNS3 vs SPNS2 — KIDNEY

Explore this scatter interactively →