Across TCGA patient cohorts, SPINK14 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,437 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SPINK14-associated proteins across cancer lineages are THEMIS2, PPP1R18, and PTPN6. Each is linked with SPINK14 in more than 4 cancer types. Because this analysis shows association rather than direction, both SPINK14-to-partner and partner-to-SPINK14 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SPINK14→partner) and Y-score (partner→SPINK14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	THEMIS2 →	-0.394	-0.489	.004	.005	3	5
LSCC	PPP1R18 →	-0.336	-1.207	<.001	<.001	3	5
GBM	PTPN6 →	-0.548	-0.659	<.001	<.001	3	5
GBM	FMNL1 →	-0.523	-0.646	<.001	<.001	3	5
HNSC	THEMIS2_T593 →	-0.675	-1.728	<.001	<.001	3	5
HNSC	TWF2 →	-0.270	-1.148	.001	.008	2	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,437 associations by consensus.

Exploration

SPINK14 survival (RNA) · tumor vs normal (RNA) · all SPINK14 data types