Across TCGA patient cohorts, SPINK14 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,799 significant associations in total. STAD shows the largest number of these associations.

The most reproducible SPINK14-associated GO terms across cancer lineages are Protein localization to endoplasmic reticulum exit site, Mitochondrial electron transport, NADH to ubiquinone, and Digestive system process. Each is linked with SPINK14 in more than 10 cancer types. Because this analysis shows association rather than direction, both SPINK14-to-partner and partner-to-SPINK14 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SPINK14→partner) and Y-score (partner→SPINK14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Protein localization to endoplasmic reticulum exit site →	+0.052	+0.305	<.001	<.001	3	11
STAD	Mitochondrial electron transport, NADH to ubiquinone →	+0.053	+0.256	<.001	<.001	3	10
STAD	Digestive system process →	+0.047	+0.192	<.001	<.001	3	10
CESC	Lobar bronchus development →	+0.067	+0.155	<.001	<.001	3	9
CESC	Lung secretory cell differentiation →	+0.073	+0.161	<.001	<.001	3	9
ESCA	ATP biosynthetic process →	+0.052	+0.418	.006	<.001	2	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,799 associations by consensus.

Exploration

SPINK14 survival (RNA) · tumor vs normal (RNA) · all SPINK14 data types