Across TCGA cell cohorts, SPINK14 RNA expression is significantly associated with the mutation status of many other genes, with 43 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible SPINK14-associated genes across cancer lineages are ATP11A, RNF32, and PNN. Each is linked with SPINK14 in more than 1 cancer types. Because this analysis shows association rather than direction, both SPINK14-to-partner and partner-to-SPINK14 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SPINK14→partner) and Y-score (partner→SPINK14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	ATP11A →	+5.285	+0.433	.003	<.001	3	2
LARGE_INTESTINE	RNF32 →	+4.977	+0.182	.007	<.001	3	1
LUNG_NSCLC_LUAD	PNN →	+4.662	+0.264	.005	<.001	3	1
LUNG_NSCLC_LUAD	NXF5 →	+5.662	+0.353	.002	<.001	3	1
LUNG_NSCLC_LUAD	MICAL2 →	+4.078	+0.211	.009	<.001	3	1
LUNG_NSCLC_LUAD	MUC4 →	+2.440	+0.075	.008	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 43 associations by consensus.

Exploration

SPINK14 survival (RNA) · tumor vs normal (RNA) · all SPINK14 data types