SPINDOC

Across TCGA cell cohorts, SPINDOC RNA expression is significantly associated with the RNA expression of many other genes, with 12,235 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SPINDOC-associated genes across cancer lineages are STIP1, CDCA5, and INCENP. Each is linked with SPINDOC in more than 19 cancer types. Because this analysis shows association rather than direction, both SPINDOC-to-partner and partner-to-SPINDOC results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SPINDOC versus STIP1 in OESOPHAGUS, with a Pearson correlation of 0.72.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SPINDOC→partner) and Y-score (partner→SPINDOC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	STIP1 →	+0.953	+1.099	<.001	<.001	3	20
PANCREAS	CDCA5 →	+1.494	+1.340	<.001	<.001	3	20
UPPER_AERODIGESTIVE_TRACT	INCENP →	+1.597	+0.938	<.001	<.001	3	20
UPPER_AERODIGESTIVE_TRACT	RBM14 →	+1.250	+0.842	<.001	<.001	3	19
LIVER	NAA40 →	+1.190	+1.052	<.001	<.001	3	19
LIVER	TAF6L →	+1.410	+1.252	<.001	<.001	3	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,235 associations by consensus.

SPINDOC vs STIP1 — OESOPHAGUS

Explore this scatter interactively →