Across TCGA patient cohorts, SPIN4 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,032 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SPIN4-associated proteins across cancer lineages are THOP1, STAG2, and HPF1. Each is linked with SPIN4 in more than 3 cancer types. Because this analysis shows association rather than direction, both SPIN4-to-partner and partner-to-SPIN4 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SPIN4→partner) and Y-score (partner→SPIN4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	THOP1 →	+0.383	+1.257	<.001	<.001	3	4
GBM	STAG2 →	+0.358	+0.550	<.001	<.001	3	4
LUAD	HPF1 →	+0.239	+0.477	<.001	<.001	3	4
GBM	MSH2 →	+0.288	+0.283	.003	.007	3	3
GBM	MSH6 →	+0.369	+0.422	.008	.002	3	3
GBM	NONO →	+0.261	+0.674	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,032 associations by consensus.

Exploration

SPIN4 survival (RNA) · tumor vs normal (RNA) · all SPIN4 data types