Across TCGA patient cohorts, SPIN4 protein abundance is significantly associated with the RNA expression of many other genes, with 752 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible SPIN4-associated genes across cancer lineages are ZNF821, ETFB, and C5orf15. Each is linked with SPIN4 in more than 1 cancer types. Because this analysis shows association rather than direction, both SPIN4-to-partner and partner-to-SPIN4 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SPIN4→partner) and Y-score (partner→SPIN4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	ZNF821 →	+0.795	+0.796	.004	.008	3	1
LUAD	ETFB →	+0.601	+0.747	.003	<.001	3	1
LUAD	C5orf15 →	+0.531	+0.747	.003	<.001	3	1
LUAD	CSNK1A1 →	+0.685	+0.747	<.001	<.001	3	1
LUAD	DYNLRB1 →	+0.753	+0.747	.005	<.001	3	1
LUAD	NDUFA2 →	+0.666	+0.747	.006	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 752 associations by consensus.

Exploration

SPIN4 survival (RNA) · tumor vs normal (RNA) · all SPIN4 data types