Across TCGA cell cohorts, SPIN4 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,845 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SPIN4-associated GO terms across cancer lineages are Mitotic spindle midzone assembly, Mitotic spindle elongation, and Spindle elongation. Each is linked with SPIN4 in more than 13 cancer types. Because this analysis shows association rather than direction, both SPIN4-to-partner and partner-to-SPIN4 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SPIN4→partner) and Y-score (partner→SPIN4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Mitotic spindle midzone assembly →	+0.228	+1.440	<.001	<.001	3	14
BREAST	Mitotic spindle elongation →	+0.228	+1.440	<.001	<.001	3	14
BLOOD_Lymphoma	Spindle elongation →	+0.231	+1.542	<.001	<.001	3	12
BREAST	Negative regulation of cell cycle process →	+0.064	+1.134	.001	.002	3	10
SOFT_TISSUE	Positive regulation of cell cycle →	+0.086	+0.866	<.001	<.001	3	10
KIDNEY	Negative regulation of mitotic metaphase/anaphase transition →	+0.135	+0.658	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,845 associations by consensus.

Exploration

SPIN4 survival (RNA) · tumor vs normal (RNA) · all SPIN4 data types