SPIN2A

Across TCGA patient cohorts, SPIN2A protein abundance is significantly associated with the RNA expression of many other genes, with 115 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible SPIN2A-associated genes across cancer lineages are RRN3P2, CPD, and DHRS7B. Each is linked with SPIN2A in more than 1 cancer types. Because this analysis shows association rather than direction, both SPIN2A-to-partner and partner-to-SPIN2A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SPIN2A versus RRN3P2 in PDAC, with a Pearson correlation of 0.66.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SPIN2A→partner) and Y-score (partner→SPIN2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	RRN3P2 →	+0.463	+2.335	.005	.001	3	1
PDAC	CPD →	+1.403	+3.286	.004	.001	3	1
PDAC	DHRS7B →	+0.640	+2.561	.003	.001	3	1
PDAC	PF4V1 →	+1.482	+2.335	.001	.001	3	1
PDAC	ATG2A →	+0.736	+2.335	.001	.001	3	1
PDAC	GYS2 →	+0.033	+2.595	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 115 associations by consensus.

SPIN2A vs RRN3P2 — PDAC

Explore this scatter interactively →