SPIN2A

Across TCGA cell cohorts, SPIN2A RNA expression is significantly associated with the go_rna of many other GO terms, with 3,693 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SPIN2A-associated GO terms across cancer lineages are mRNA splice site recognition, Positive regulation of intracellular steroid hormone receptor signaling pathway, and Pre-mRNA catabolic process. Each is linked with SPIN2A in more than 14 cancer types. Because this analysis shows association rather than direction, both SPIN2A-to-partner and partner-to-SPIN2A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, mRNA splice site recognition grouped by SPIN2A-low versus SPIN2A-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SPIN2A→partner) and Y-score (partner→SPIN2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	mRNA splice site recognition →	+0.148	+0.517	<.001	<.001	3	15
LARGE_INTESTINE	Positive regulation of intracellular steroid hormone receptor signaling pathway →	+0.152	+0.413	<.001	<.001	3	14
BONE	Pre-mRNA catabolic process →	+0.194	+0.756	<.001	.002	3	14
SOFT_TISSUE	Spliceosomal complex assembly →	+0.087	+0.295	<.001	<.001	3	13
SOFT_TISSUE	Regulation of RNA splicing →	+0.065	+0.217	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Protein localization to cytoplasmic stress granule →	+0.128	+0.321	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,693 associations by consensus.

mRNA splice site recognition by SPIN2A expression — LARGE_INTESTINE

Explore this box plot interactively →