Across TCGA patient cohorts, SPG7 RNA expression is significantly associated with the RNA expression of many other genes, with 19,493 significant associations in total. UVM shows the largest number of these associations.

The most reproducible SPG7-associated genes across cancer lineages are CENPT, TAF1C, and KLHDC4. Each is linked with SPG7 in more than 33 cancer types. Because this analysis shows association rather than direction, both SPG7-to-partner and partner-to-SPG7 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SPG7→partner) and Y-score (partner→SPG7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIRC	CENPT →	+1.050	+0.679	<.001	<.001	3	34
SCLC	TAF1C →	+1.706	+0.937	<.001	<.001	3	34
SCLC	KLHDC4 →	+0.946	+1.183	<.001	<.001	3	34
SCLC	ZNF276 →	+1.242	+1.113	<.001	<.001	3	34
SCLC	WDR59 →	+1.035	+1.225	<.001	<.001	3	34
SCLC	STX16 →	+1.188	+1.255	.001	<.001	3	34

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,493 associations by consensus.

Exploration

SPG7 survival (RNA) · tumor vs normal (RNA) · all SPG7 data types