Across TCGA cell cohorts, SPG7 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,747 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SPG7-associated GO terms across cancer lineages are Nucleic acid transport, RNA transport, and Establishment of RNA localization. Each is linked with SPG7 in more than 16 cancer types. Because this analysis shows association rather than direction, both SPG7-to-partner and partner-to-SPG7 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SPG7→partner) and Y-score (partner→SPG7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Nucleic acid transport →	+0.091	+0.852	<.001	<.001	3	17
BONE	RNA transport →	+0.091	+0.852	<.001	<.001	3	17
BONE	Establishment of RNA localization →	+0.094	+1.040	<.001	<.001	3	17
OESOPHAGUS	mRNA splice site recognition →	+0.182	+1.037	<.001	<.001	3	17
OESOPHAGUS	RNA localization →	+0.092	+0.697	.007	.004	3	17
BONE	Regulation of transcription of nucleolar large rRNA by RNA polymerase I →	+0.190	+1.242	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,747 associations by consensus.

Exploration

SPG7 survival (RNA) · tumor vs normal (RNA) · all SPG7 data types