SPEM1

Across TCGA cell cohorts, SPEM1 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,516 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible SPEM1-associated GO terms across cancer lineages are Regulation of respiratory gaseous exchange by nervous system process, Postsynaptic density protein 95 clustering, and Thigmotaxis. Each is linked with SPEM1 in more than 9 cancer types. Because this analysis shows association rather than direction, both SPEM1-to-partner and partner-to-SPEM1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of respiratory gaseous exchange by nervous system process grouped by SPEM1-low versus SPEM1-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SPEM1→partner) and Y-score (partner→SPEM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Regulation of respiratory gaseous exchange by nervous system process →	+1.157	+0.195	<.001	.008	3	10
OESOPHAGUS	Postsynaptic density protein 95 clustering →	+1.392	+0.195	<.001	.008	3	9
LUNG_NSCLC_LUAD	Thigmotaxis →	+0.164	+0.045	<.001	<.001	3	8
STOMACH	Regulation of termination of RNA polymerase II transcription →	+0.131	+0.067	<.001	.005	3	8
STOMACH	Regulation of termination of RNA polymerase II transcription, poly(A)-coupled →	+0.132	+0.067	<.001	.005	3	8
STOMACH	Regulation of termination of DNA-templated transcription →	+0.131	+0.067	<.001	.005	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,516 associations by consensus.

Regulation of respiratory gaseous exchange by nervous system process by SPEM1 expression — OESOPHAGUS

Explore this box plot interactively →