Across TCGA patient cohorts, SPDYE4 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,913 significant associations in total. STAD shows the largest number of these associations.

The most reproducible SPDYE4-associated GO terms across cancer lineages are Protein polyubiquitination, Regulation of ubiquitin-dependent protein catabolic process, and Protein-containing complex disassembly. Each is linked with SPDYE4 in more than 23 cancer types. Because this analysis shows association rather than direction, both SPDYE4-to-partner and partner-to-SPDYE4 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SPDYE4→partner) and Y-score (partner→SPDYE4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Protein polyubiquitination →	+0.059	+0.092	<.001	.002	3	24
ESCA	Regulation of ubiquitin-dependent protein catabolic process →	+0.061	+0.082	<.001	.001	3	24
ESCA	Protein-containing complex disassembly →	+0.046	+0.075	<.001	<.001	2	24
ESCA	Positive regulation of canonical NF-kappaB signal transduction →	+0.065	+0.097	<.001	<.001	3	23
ESCA	Positive regulation of protein catabolic process →	+0.049	+0.071	.001	<.001	3	23
STAD	Glycerophospholipid biosynthetic process →	+0.033	+0.052	<.001	<.001	3	23

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,913 associations by consensus.

Exploration

SPDYE4 survival (RNA) · tumor vs normal (RNA) · all SPDYE4 data types