SPDYE4

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, SPDYE4 RNA expression is significantly associated with the go_rna of many other GO terms, with 366 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible SPDYE4-associated GO terms across cancer lineages are Regulation of exosomal secretion, Positive regulation of exosomal secretion, and Regulation of actomyosin structure organization. Each is linked with SPDYE4 in more than 3 cancer types. Because this analysis shows association rather than direction, both SPDYE4-to-partner and partner-to-SPDYE4 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SPDYE4→partner) and Y-score (partner→SPDYE4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKINRegulation of exosomal secretion →+0.093+0.007.001.00834
SKINPositive regulation of exosomal secretion →+0.074+0.010.003.00633
BLOOD_LeukemiaRegulation of actomyosin structure organization →+0.031+0.046.001.00633
BLOOD_LeukemiaResponse to type I interferon →+0.049+0.068<.001.00633
BLOOD_LeukemiaNeuroepithelial cell differentiation →+0.109+0.092.006.00333
SKINAttachment of GPI anchor to protein →+0.093+0.007.004.00832
Each partner links to its Q-omics profile. Showing the 6 strongest of 366 associations by consensus.

Exploration