Across TCGA patient cohorts, SPDYE16 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,336 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible SPDYE16-associated proteins across cancer lineages are GET3, WNK2_S1862, and ZNF318_S1616. Each is linked with SPDYE16 in more than 2 cancer types. Because this analysis shows association rather than direction, both SPDYE16-to-partner and partner-to-SPDYE16 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SPDYE16→partner) and Y-score (partner→SPDYE16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	GET3 →	+0.356	+0.287	.002	.003	3	3
LSCC	WNK2_S1862 →	+0.943	+0.268	.002	.006	3	3
HNSC	ZNF318_S1616 →	+0.729	+0.985	<.001	.004	3	2
LSCC	ZNF318_S2101 →	+0.462	+0.334	.007	.001	3	2
BRCA	ZNF512B →	+0.398	+0.121	.005	.002	3	2
PDAC	ZNF687_S1191 →	+0.524	+0.208	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,336 associations by consensus.

Exploration

SPDYE16 survival (RNA) · tumor vs normal (RNA) · all SPDYE16 data types