SPDYE12P

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SPDYE12P RNA expression is significantly associated with the protein abundance of many other proteins, with 12,367 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SPDYE12P-associated proteins across cancer lineages are MEPCE, IGKC, and PLCG2. Each is linked with SPDYE12P in more than 4 cancer types. Because this analysis shows association rather than direction, both SPDYE12P-to-partner and partner-to-SPDYE12P results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SPDYE12P→partner) and Y-score (partner→SPDYE12P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCMEPCE →+0.283+0.426<.001<.00135
GBMIGKC →-0.411-0.350<.001<.00135
GBMPLCG2 →-0.694-0.517<.001<.00135
PDACDCAF7 →+0.225+0.262<.001<.00135
LSCCFKBP11 →-0.689-0.558<.001<.00135
GBMGTF3C4 →+0.326+0.476<.001<.00135
Each partner links to its Q-omics profile. Showing the 6 strongest of 12,367 associations by consensus.

Exploration