SPCS2P3

Across TCGA patient cohorts, SPCS2P3 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,225 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SPCS2P3-associated proteins across cancer lineages are WNK2_S1862, ZYX, and C1orf226_S198. Each is linked with SPCS2P3 in more than 4 cancer types. Because this analysis shows association rather than direction, both SPCS2P3-to-partner and partner-to-SPCS2P3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SPCS2P3 versus WNK2_S1862 in LUAD, with a Pearson correlation of 0.30.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SPCS2P3→partner) and Y-score (partner→SPCS2P3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	WNK2_S1862 →	+0.788	+0.632	<.001	<.001	3	5
GBM	ZYX →	-0.303	-0.354	<.001	<.001	3	4
LUAD	C1orf226_S198 →	+1.242	+0.794	<.001	<.001	3	3
HNSC	CAMSAP3_S1020 →	+0.654	+0.770	<.001	.001	3	3
GBM	AFAP1L1_S98 →	-0.592	-0.370	.003	<.001	3	3
LUAD	DCAF7 →	+0.210	+0.508	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,225 associations by consensus.

SPCS2P3 vs WNK2_S1862 — LUAD

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