SPATS2

Across TCGA patient cohorts, SPATS2 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,435 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SPATS2-associated proteins across cancer lineages are DDX23, EPS8L2, and ZNF428. Each is linked with SPATS2 in more than 5 cancer types. Because this analysis shows association rather than direction, both SPATS2-to-partner and partner-to-SPATS2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SPATS2 versus DDX23 in LSCC, with a Pearson correlation of 0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SPATS2→partner) and Y-score (partner→SPATS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	DDX23 →	+0.250	+0.347	<.001	.002	3	6
GBM	EPS8L2 →	-0.827	-0.553	<.001	<.001	3	6
GBM	ZNF428 →	+0.355	+0.352	<.001	.001	3	5
HNSC	MYG1 →	+0.199	+0.544	<.001	<.001	3	5
LUAD	NASP_S451 →	+1.363	+0.516	.001	<.001	3	5
HNSC	ARID2 →	+0.264	+0.707	.001	.004	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,435 associations by consensus.

SPATS2 vs DDX23 — LSCC

Explore this scatter interactively →