SPATS1

Across TCGA cell cohorts, SPATS1 RNA expression is significantly associated with the go_rna of many other GO terms, with 885 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible SPATS1-associated GO terms across cancer lineages are Energy derivation by oxidation of organic compounds, Regulation of phospholipase activity, and Positive regulation of phospholipase activity. Each is linked with SPATS1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SPATS1-to-partner and partner-to-SPATS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Energy derivation by oxidation of organic compounds grouped by SPATS1-low versus SPATS1-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SPATS1→partner) and Y-score (partner→SPATS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Energy derivation by oxidation of organic compounds →	+0.040	+1.322	.008	.001	3	2
SKIN	Regulation of phospholipase activity →	-1.109	-1.028	<.001	.004	3	1
SKIN	Positive regulation of phospholipase activity →	-1.109	-1.028	<.001	.004	3	1
SKIN	Regulation of vesicle docking →	+0.204	+1.324	<.001	<.001	3	1
SKIN	Aminoacyl-tRNA metabolism involved in translational fidelity →	+0.079	+1.246	<.001	<.001	3	1
SKIN	Positive regulation of macrophage derived foam cell differentiation →	-0.246	-1.587	.009	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 885 associations by consensus.

Energy derivation by oxidation of organic compounds by SPATS1 expression — SKIN

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