SPATA7

Across TCGA patient cohorts, SPATA7 mutation is significantly associated with the RNA expression of many other genes, with 1,461 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SPATA7-associated genes across cancer lineages are RN7SKP286, ZMAT1, and RPL32P22. Each is linked with SPATA7 in more than 2 cancer types. Because this analysis shows association rather than direction, both SPATA7-to-partner and partner-to-SPATA7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SKP286 grouped by SPATA7-low versus SPATA7-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SPATA7→partner) and Y-score (partner→SPATA7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SKP286 →	+0.042	+3.945	<.001	<.001	3	3
UCEC	ZMAT1 →	-0.505	-1.652	.009	.006	3	2
SKCM	RPL32P22 →	+0.147	+2.571	.009	.004	3	2
UCEC	SDCBP2 →	+0.901	+2.103	<.001	.003	3	2
BLCA	RPSAP27 →	+0.038	+3.020	.003	.006	3	2
BLCA	RNU6-276P →	+0.239	+4.722	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,461 associations by consensus.

RN7SKP286 by SPATA7 expression — UCEC

Explore this box plot interactively →