SPATA6L

Across TCGA patient cohorts, SPATA6L RNA expression is significantly associated with the protein abundance of many other proteins, with 16,688 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible SPATA6L-associated proteins across cancer lineages are VWA5A, RFX3_S155, and DDAH1. Each is linked with SPATA6L in more than 5 cancer types. Because this analysis shows association rather than direction, both SPATA6L-to-partner and partner-to-SPATA6L results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SPATA6L versus VWA5A in HNSC, with a Pearson correlation of 0.32.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SPATA6L→partner) and Y-score (partner→SPATA6L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	VWA5A →	+0.448	+0.634	<.001	.003	3	6
LSCC	RFX3_S155 →	+0.645	+0.660	<.001	<.001	3	6
HNSC	DDAH1 →	+0.785	+0.905	<.001	<.001	3	6
OV	SETMAR →	+0.398	+0.632	.001	<.001	3	5
HNSC	SMARCA2 →	+0.375	+0.749	<.001	<.001	3	5
BRCA	MTARC2 →	+0.706	+0.864	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,688 associations by consensus.

SPATA6L vs VWA5A — HNSC

Explore this scatter interactively →