SPATA6L

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, SPATA6L RNA expression is significantly associated with the go_rna of many other GO terms, with 4,242 significant associations in total. BONE shows the largest number of these associations.

The most reproducible SPATA6L-associated GO terms across cancer lineages are Regulation of myoblast fusion, Regulation of syncytium formation by plasma membrane fusion, and Autophagosome membrane docking. Each is linked with SPATA6L in more than 9 cancer types. Because this analysis shows association rather than direction, both SPATA6L-to-partner and partner-to-SPATA6L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of myoblast fusion grouped by SPATA6L-low versus SPATA6L-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SPATA6L→partner) and Y-score (partner→SPATA6L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUNG_SCLCRegulation of myoblast fusion →+0.101+0.817<.001.007310
LUNG_SCLCRegulation of syncytium formation by plasma membrane fusion →+0.106+1.027<.001.001310
LIVERAutophagosome membrane docking →+0.095+0.708.003.00739
LUNG_SCLCRegulation of nucleocytoplasmic transport →+0.068+1.068.001<.00139
STOMACHRegulation of artery morphogenesis →+0.176+1.250.004.00238
STOMACHPositive regulation of artery morphogenesis →+0.176+1.250.004.00238
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,242 associations by consensus.

Regulation of myoblast fusion by SPATA6L expression — LUNG_SCLC

Box plot of Regulation of myoblast fusion in SPATA6L-low vs SPATA6L-high samples in LUNG_SCLC.

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Exploration