SPATA6L

Across TCGA cell cohorts, SPATA6L mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SPATA6L-associated genes across cancer lineages are SPHKAP and FCN2. Each is linked with SPATA6L in more than 1 cancer types. Because this analysis shows association rather than direction, both SPATA6L-to-partner and partner-to-SPATA6L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SPHKAP grouped by SPATA6L-low versus SPATA6L-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SPATA6L→partner) and Y-score (partner→SPATA6L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	SPHKAP →	+0.006	+5.415	.007	.004	3	1
LARGE_INTESTINE	FCN2 →	+0.052	+5.415	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

SPHKAP by SPATA6L expression — LARGE_INTESTINE

Explore this box plot interactively →