SPATA46

Across TCGA patient cohorts, SPATA46 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,028 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SPATA46-associated proteins across cancer lineages are C1orf226_S223, C1orf226_S198, and NOS1AP. Each is linked with SPATA46 in more than 8 cancer types. Because this analysis shows association rather than direction, both SPATA46-to-partner and partner-to-SPATA46 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SPATA46 versus C1orf226_S223 in BRCA, with a Pearson correlation of 0.57.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SPATA46→partner) and Y-score (partner→SPATA46) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	C1orf226_S223 →	+1.084	+1.420	<.001	<.001	3	9
BRCA	C1orf226_S198 →	+1.312	+1.478	<.001	<.001	3	8
BRCA	NOS1AP →	+0.950	+1.156	<.001	<.001	3	7
BRCA	C1orf226_S222 →	+1.412	+1.780	<.001	<.001	3	6
LSCC	ADAR →	+0.257	+0.690	<.001	<.001	3	6
UCEC	PARP1 →	+0.396	+0.831	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,028 associations by consensus.

SPATA46 vs C1orf226_S223 — BRCA

Explore this scatter interactively →