Across TCGA patient cohorts, SPATA32 mutation is significantly associated with the RNA expression of many other genes, with 92 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible SPATA32-associated genes across cancer lineages are RN7SKP261, RN7SL692P, and SLC25A31. Each is linked with SPATA32 in more than 1 cancer types. Because this analysis shows association rather than direction, both SPATA32-to-partner and partner-to-SPATA32 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SPATA32→partner) and Y-score (partner→SPATA32) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RN7SKP261 →	+0.273	+5.584	<.001	.003	3	2
BLCA	RN7SL692P →	+0.239	+4.899	<.001	.005	3	2
SKCM	SLC25A31 →	+0.036	+3.423	.008	<.001	3	2
BLCA	RNA5SP72 →	+0.511	+5.762	<.001	<.001	3	2
STAD	RPS29P1 →	+0.410	+4.254	.003	.008	3	2
GBM	LINC02745 →	+0.120	+5.352	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 92 associations by consensus.

Exploration

SPATA32 survival (RNA) · tumor vs normal (RNA) · all SPATA32 data types