Across TCGA pan-cancer cohorts, SPATA32 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of SPATA32’s most consistent transcriptional readouts.
The strongest signal is observed in bladder urothelial carcinoma (BLCA), where SPATA32 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types SPATA32 is over-expressed in tumor, although a few such as KICH and COAD show the opposite, repressed pattern.
BLCA, STAD, and KIRC are the cancer types where SPATA32 tumor–normal differential expression is most reproducible.
RNA tumor vs normal associations by lineage
Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SPATA32 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.