SPATA31E1

Across TCGA patient cohorts, SPATA31E1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,878 significant associations in total. STAD shows the largest number of these associations.

The most reproducible SPATA31E1-associated GO terms across cancer lineages are Epigenetic regulation of gene expression, Regulation of post-translational protein modification, and Lytic vacuole organization. Each is linked with SPATA31E1 in more than 15 cancer types. Because this analysis shows association rather than direction, both SPATA31E1-to-partner and partner-to-SPATA31E1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Epigenetic regulation of gene expression grouped by SPATA31E1-low versus SPATA31E1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SPATA31E1→partner) and Y-score (partner→SPATA31E1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Epigenetic regulation of gene expression →	+0.058	+0.058	<.001	<.001	3	16
STAD	Regulation of post-translational protein modification →	+0.059	+0.062	<.001	<.001	3	16
STAD	Lytic vacuole organization →	+0.060	+0.068	<.001	<.001	3	15
STAD	Cytoskeleton-dependent intracellular transport →	+0.043	+0.069	<.001	<.001	3	15
ESCA	Methylation →	+0.057	+0.099	<.001	<.001	2	16
STAD	TORC1 signaling →	+0.063	+0.062	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,878 associations by consensus.

Epigenetic regulation of gene expression by SPATA31E1 expression — STAD

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