SPATA31E1

Across TCGA pan-cancer cohorts, SPATA31E1 RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of SPATA31E1’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where SPATA31E1 RNA is repressed in tumor relative to normal tissue. In most cancer types SPATA31E1 is over-expressed in tumor, although a few such as COAD and BLCA show the opposite, repressed pattern.

COAD, KIRC, and BLCA are the cancer types where SPATA31E1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SPATA31E1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	All	−0.058	<.001	11	view →
KIRC	All	All	+0.020	<.001	4	view →
BLCA	Male	IV	−0.100	.002	2	view →
READ	All	All	−0.048	.013	2	view →
PRAD	All	All	+0.009	.002	2	view →
LIHC	All	All	+0.005	.015	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

SPATA31E1–COAD

Open the COAD breakdown →