Across TCGA patient cohorts, SPATA31D1 mutation is significantly associated with the RNA expression of many other genes, with 6,679 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SPATA31D1-associated genes across cancer lineages are CYSLTR1, LRRC34P2, and EMC9. Each is linked with SPATA31D1 in more than 4 cancer types. Because this analysis shows association rather than direction, both SPATA31D1-to-partner and partner-to-SPATA31D1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SPATA31D1→partner) and Y-score (partner→SPATA31D1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	CYSLTR1 →	-0.560	-1.388	<.001	.003	3	5
BLCA	LRRC34P2 →	+0.051	+4.466	<.001	.003	3	5
UCEC	EMC9 →	+0.362	+1.321	<.001	.002	3	5
UCEC	PPP2R5D →	+0.493	+2.850	<.001	<.001	3	5
UCEC	HAUS8 →	+0.384	+2.000	<.001	<.001	3	5
LUSC	CYYR1 →	-0.539	-1.676	.001	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,679 associations by consensus.

Exploration

SPATA31D1 survival (RNA) · tumor vs normal (RNA) · all SPATA31D1 data types