Across TCGA pan-cancer cohorts, SPATA31D1 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of SPATA31D1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where SPATA31D1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types SPATA31D1 is over-expressed in tumor.

KIRC and LIHC are the cancer types where SPATA31D1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SPATA31D1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	All	+0.011	.001	4	view →
LIHC	All	All	+0.090	.019	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: SPATA31D1 RNA expression & survival · all SPATA31D1 data types