Across TCGA patient cohorts, SPATA31D1 mutation is significantly associated with the total protein of many other genes, with 86 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SPATA31D1-associated genes across cancer lineages are NF2, ACC_pS79, and ACVRL1. Each is linked with SPATA31D1 in more than 3 cancer types. Because this analysis shows association rather than direction, both SPATA31D1-to-partner and partner-to-SPATA31D1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SPATA31D1→partner) and Y-score (partner→SPATA31D1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	NF2 →	+0.275	+3.000	.031	.035	3	4
LUAD	ACC_pS79 →	+0.336	+3.459	.003	.004	3	3
COAD	ACVRL1 →	-0.251	-1.798	.006	.026	3	3
UCEC	Heregulin →	-0.096	-1.392	.007	.017	3	3
UCEC	ASNS →	+0.225	+1.321	.032	.027	3	3
UCEC	Di-Ras3 →	-0.148	-2.986	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 86 associations by consensus.

Exploration

SPATA31D1 survival (RNA) · tumor vs normal (RNA) · all SPATA31D1 data types