Across TCGA cell cohorts, SPATA31D1 mutation is significantly associated with the RNA expression of many other genes, with 525 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SPATA31D1-associated genes across cancer lineages are CELA2B, OR3A2, and KLF11. Each is linked with SPATA31D1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SPATA31D1-to-partner and partner-to-SPATA31D1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SPATA31D1→partner) and Y-score (partner→SPATA31D1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	CELA2B →	+0.081	+4.108	<.001	.005	3	2
LUNG_NSCLC_LUSC	OR3A2 →	+0.404	+4.108	.006	.005	3	2
LUNG_NSCLC_LUAD	KLF11 →	-0.710	-2.459	<.001	.008	3	2
BLOOD_Leukemia	GADL1 →	+0.472	+2.662	<.001	.001	3	2
BLOOD_Leukemia	IQCB1 →	+0.486	+3.120	.001	.009	3	2
BLOOD_Leukemia	ZNF48 →	+0.683	+3.489	.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 525 associations by consensus.

Exploration

SPATA31D1 survival (RNA) · tumor vs normal (RNA) · all SPATA31D1 data types