Across TCGA patient cohorts, SPATA31A6 mutation is significantly associated with the RNA expression of many other genes, with 2,943 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible SPATA31A6-associated genes across cancer lineages are MED27, DBF4, and WDR62. Each is linked with SPATA31A6 in more than 3 cancer types. Because this analysis shows association rather than direction, both SPATA31A6-to-partner and partner-to-SPATA31A6 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SPATA31A6→partner) and Y-score (partner→SPATA31A6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	MED27 →	+0.434	+3.478	.001	.002	3	4
SKCM	DBF4 →	+0.722	+2.851	.003	.001	3	4
LUAD	WDR62 →	+0.588	+1.830	.002	.002	3	4
LUSC	SPAG5 →	+0.626	+2.842	.001	.001	3	4
LUAD	UBE2T →	+0.641	+2.339	.003	.003	3	4
LUAD	EME1 →	+0.472	+1.915	.008	.009	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,943 associations by consensus.

Exploration

SPATA31A6 survival (RNA) · tumor vs normal (RNA) · all SPATA31A6 data types