Across TCGA pan-cancer cohorts, SPATA31A6 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of SPATA31A6’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where SPATA31A6 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types SPATA31A6 is over-expressed in tumor.

BRCA, LUSC, and STAD are the cancer types where SPATA31A6 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SPATA31A6 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	All	II,III,IV	+0.014	.016	4	view →
LUSC	All	All	+0.020	.003	3	view →
STAD	All	All	+0.009	.044	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: SPATA31A6 RNA expression & survival · all SPATA31A6 data types