Across TCGA patient cohorts, SPATA31A6 mutation is significantly associated with the total protein of many other genes, with 22 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SPATA31A6-associated genes across cancer lineages are XRCC1, Ret_pY905, and ASNS. Each is linked with SPATA31A6 in more than 2 cancer types. Because this analysis shows association rather than direction, both SPATA31A6-to-partner and partner-to-SPATA31A6 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SPATA31A6→partner) and Y-score (partner→SPATA31A6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	XRCC1 →	+0.137	+2.594	.045	.006	3	3
LUSC	Ret_pY905 →	-0.211	-2.921	.030	.035	3	2
LUSC	ASNS →	+0.442	+1.883	.018	.031	3	2
UCEC	ACC_pS79 →	+0.357	+2.179	.015	.034	3	2
UCEC	Rictor_pT1135 →	-0.097	-1.700	.026	.044	3	2
UCEC	SF2 →	-0.092	-1.687	.046	.044	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 22 associations by consensus.

Exploration

SPATA31A6 survival (RNA) · tumor vs normal (RNA) · all SPATA31A6 data types