SPATA31A6

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, SPATA31A6 mutation is significantly associated with the RNA expression of many other genes, with 26 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible SPATA31A6-associated genes across cancer lineages are TAAR8, CD300H, and LY9. Each is linked with SPATA31A6 in more than 1 cancer types. Because this analysis shows association rather than direction, both SPATA31A6-to-partner and partner-to-SPATA31A6 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SPATA31A6→partner) and Y-score (partner→SPATA31A6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUNG_NSCLC_LUADTAAR8 →+0.017+4.662<.001.00532
LARGE_INTESTINECD300H →+0.045+5.415<.001.00431
LUNG_SCLCLY9 →+0.142+3.479<.001.00731
LUNG_SCLCMAJIN →+0.588+3.928<.001.00131
LUNG_SCLCUMOD →+0.157+3.887.002.00131
LUNG_SCLCOR10AC1 →+0.045+3.099.001.00331
Each partner links to its Q-omics profile. Showing the 6 strongest of 26 associations by consensus.

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