SPATA3-AS1

Across TCGA pan-cancer cohorts, SPATA3-AS1 RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of SPATA3-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where SPATA3-AS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types SPATA3-AS1 is over-expressed in tumor, although a few such as KICH show the opposite, repressed pattern.

COAD, STAD, and LIHC are the cancer types where SPATA3-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SPATA3-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	III,IV	+0.709	<.001	11	view →
STAD	All	All	+0.226	.002	6	view →
LIHC	All	II,III,IV	+0.084	<.001	6	view →
LUAD	Female	All	+0.083	<.001	5	view →
KICH	All	All	−0.030	.003	5	view →
LUSC	All	All	+0.146	<.001	4	view →
READ	All	All	+0.522	.003	3	view →
KIRP	All	II,III,IV	+0.169	.020	3	view →
CHOL	All	All	+0.415	.008	2	view →
PRAD	All	All	+0.163	<.001	2	view →
UCEC	All	All	+0.070	.029	2	view →
THCA	All	All	+0.065	.031	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

SPATA3-AS1–COAD

Open the COAD breakdown →