SPATA25

Across TCGA patient cohorts, SPATA25 mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SPATA25-associated genes across cancer lineages are CD8+ Tcm and CD8+ Tem. Each is linked with SPATA25 in more than 1 cancer types. Because this analysis shows association rather than direction, both SPATA25-to-partner and partner-to-SPATA25 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD8+ Tcm grouped by SPATA25-low versus SPATA25-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SPATA25→partner) and Y-score (partner→SPATA25) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CD8+ Tcm →	+0.085	+3.935	<.001	.003	3	1
UCEC	CD8+ Tem →	+0.007	+5.744	<.001	.022	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

CD8+ Tcm by SPATA25 expression — UCEC

Explore this box plot interactively →