SPATA2

Across TCGA patient cohorts, SPATA2 protein abundance is significantly associated with the RNA expression of many other genes, with 6,643 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SPATA2-associated genes across cancer lineages are PUM3, TRIM59, and SLC25A22. Each is linked with SPATA2 in more than 2 cancer types. Because this analysis shows association rather than direction, both SPATA2-to-partner and partner-to-SPATA2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SPATA2 versus PUM3 in LSCC, with a Pearson correlation of -0.28.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SPATA2→partner) and Y-score (partner→SPATA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PUM3 →	-0.429	-0.210	.006	.001	3	3
LUAD	TRIM59 →	-0.571	-0.329	.001	.001	3	3
PDAC	SLC25A22 →	-0.540	-0.341	<.001	.001	3	3
GBM	ATP1A2 →	+2.092	+0.235	<.001	.001	3	3
HNSC	MADD-AS1 →	-0.944	-0.351	.005	.002	3	3
GBM	ATP8A2 →	+1.400	+0.323	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,643 associations by consensus.

SPATA2 vs PUM3 — LSCC

Explore this scatter interactively →