SPATA13

Across TCGA patient cohorts, SPATA13 protein abundance is significantly associated with the protein abundance of many other proteins, with 8,918 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SPATA13-associated proteins across cancer lineages are PLEKHO2, ARPC5, and DOK1. Each is linked with SPATA13 in more than 2 cancer types. Because this analysis shows association rather than direction, both SPATA13-to-partner and partner-to-SPATA13 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SPATA13 versus PLEKHO2 in LSCC, with a Pearson correlation of 0.53.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SPATA13→partner) and Y-score (partner→SPATA13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PLEKHO2 →	+0.296	+0.506	<.001	<.001	3	3
LSCC	ARPC5 →	+0.235	+0.357	<.001	<.001	3	3
GBM	DOK1 →	+0.228	+0.358	.001	.006	3	3
LSCC	WAS →	+0.392	+0.462	<.001	<.001	3	3
GBM	RBBP7 →	-0.322	-0.461	<.001	.004	2	3
LSCC	ARHGEF5_S1004 →	-1.020	-0.538	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,918 associations by consensus.

SPATA13 vs PLEKHO2 — LSCC

Explore this scatter interactively →