SPATA13

Across TCGA patient cohorts, SPATA13 mutation is significantly associated with the RNA expression of many other genes, with 2,964 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SPATA13-associated genes across cancer lineages are LINC02222, RNU6-446P, and TLE6. Each is linked with SPATA13 in more than 1 cancer types. Because this analysis shows association rather than direction, both SPATA13-to-partner and partner-to-SPATA13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC02222 grouped by SPATA13-low versus SPATA13-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SPATA13→partner) and Y-score (partner→SPATA13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	LINC02222 →	+0.035	+5.252	<.001	.002	3	2
LIHC	RNU6-446P →	+0.192	+4.423	.002	.007	3	2
UCEC	TLE6 →	+0.798	+1.975	<.001	<.001	3	2
COAD	MCUB →	+0.943	+3.210	<.001	.009	3	2
BRCA	LINC01707 →	+0.105	+3.975	<.001	.005	3	2
SKCM	RN7SKP196 →	+0.053	+4.671	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,964 associations by consensus.

LINC02222 by SPATA13 expression — CESC

Explore this box plot interactively →